Current issues in statistics and models for Ecotoxicological Risk Assessment.
Nelly van der Hoeven
ECOSTAT
Vondellaan 23
2332 AA Leiden
The Netherlands
NvdH @iecostat.nl
and
Leiden University, IEES,
Department of Theoretical Evolutionary Biology,
P.O. Box 9516,
2300 RA Leiden,
The Netherlands
Abstract
A review is given on statistical and modelling issues in ecotoxicology. The issues discussed are:
-
How to estimate an (almost) no effect concentration in the laboratory
- Combining single-species acceptable effect levels to an acceptable effect level for a multi-species ecosystem.
- The combined effect of exposure to several chemicals.
- Bioavailability in the natural environment and food-web models.
Most current procedures in setting standards allow the environmental concentration to be above the acceptable effect concentration for a small fraction of the species. It is shown that a considerable part of the fraction of the affected species will suffer a severe effect.
Keywords: bioaccumulation; bioavailability; combination toxicology; ECx; equilibrium partition; food-web models; hazardous concentration; NOEC; Species Sensitivity Distribution; Toxic Units
Acta Biotheoretica 52: 201-217, 2004